You Can't Spell C U R E Without "The U"

Twenty-four University of Miami research teams have received rapid response grants to undertake innovative projects that will provide critical information about the novel coronavirus.

Imagine this: developing an oral rinse test to detect COVID-19 earlier, creating a behavior therapy program for parents so that they do not pass on the stress they are feeling to their children during the pandemic, and gauging the effects of COVID-19 on pregnant women and trying to determine the impacts on their new babies. 

These are just a few of the 24 projects recently awarded rapid response grants from the University of Miami’s Office of the Vice Provost for Research. The grants, which range from $5,000 to $40,000, require faculty members and students to develop and execute research that will somehow broaden our understanding of COVID-19 and begin to mitigate its impacts within the next four months.

“Our idea was to take advantage of researchers’ creativity and commitment in tackling some of the most pressing problems around the COVID-19 epidemic,” said John Bixby, vice provost for research and professor of molecular and cellular pharmacology and neurological surgery. “We challenged them to examine the effects of the pandemic on multiple aspects of people’s lives—not just the physical ones, but the social aspects, the economic ones, and the environmental.”

With just 10 days to submit proposals, faculty members across the university flooded the office with applications and more than 70 ideas were submitted. Each award was reviewed by three individuals, and the awardees were selected based on novelty, potential impact on the effort to combat COVID-19, and whether the study could be completed in short turnaround time.

“The faculty response was inspiring,” said Erin Kobetz, co-vice provost for research. “There was a level of innovation across multiple disciplines that demonstrates an institutional commitment to addressing the COVID-19 pandemic. We look forward to the outcomes of those applications that were funded and imagine that they will lead to positive, measurable impact now and in the future.”

After the four months are over, teams will be asked to report their progress, Bixby said. Below is a list of all the projects awarded grants:

• Double-Blind, Randomized Study to Assess the Efficacy and Safety of Pulsed, Inhaled Nitric Oxide (iNO) in Subjects with Coronavirus Disease (COVID-19) Requiring Supplemental Oxygen

This team will evaluate the potential benefits of nitric oxide in treating COVID-19 utilizing the iNOpulse technology, which may potentially allow future patients to be treated outside of the hospital.

Principal investigator: Roger Alvarez, assistant professor of clinical medicine,

• Generating a COVID/SARS VSV Based Vaccine

This team will develop a novel vaccine to protect against the current coronavirus pandemic caused by SARS-CoV-2. Its strategy involves replacing the envelope glycoprotein (G) of vesicular stomatitis virus (VSV) with the spike of COVID-19. The resulting virus will form the basis of a vaccine to generate neutralizing antibody to the SARS-CoV-2 spike that could prevent disease if exposed to the real virus.

Principal investigator: Glen Barber, professor and chair of cell biology

• Fast-Tracking COVID-19 Treatment: Exploiting the Androgen Receptor/TMPRSS2 Axis

This study will exploit the enzyme TMPRSS2 as a potential link between androgen receptors and COVID-19 by providing preliminary data on whether certain drugs—called androgen receptor antagonists—that are effective and safe for treating prostate cancer, might also be effective in treating COVID-19.

Principal investigator: Kerry Burnstein, professor of molecular and cellular pharmacology

• CORONA: An Engaged Participatory Art Project to Assess the Impact of COVID-19 in Miami.

Artist Xavier Cortada will develop a socially engaged art platform online to mitigate stress related to COVID-19 infection and/or social distancing. He is also working to develop participatory art projects and an online message mural to capture stories from individuals across South Florida as they are affected by the pandemic. https://cortadaprojects.org/projects/corona/

Principal investigator: Xavier Cortada, professor of practice, art and art history

• Risk and Resiliency in the Early Childhood Community in Response to the Coronavirus Pandemic

Public health emergencies pose huge challenges to the behavioral health system, and consequences on the psychosocial well-being of people in at-risk communities largely go overlooked. This project will first identify community psychosocial needs and then create and disseminate a multilingual COVID-19 online toolkit and resource hub to mitigate negative mental health outcomes throughout the pandemic.

Principal investigator: Bridget Davidson, assistant professor of clinical pediatrics

• Interactive Online Cultural Experience and Technologically Innovative Social Engagement for Older and Vulnerable Populations to Mitigate Stress Caused by Social Distancing During the Covid-19 Pandemic

This team will develop a prototype for a socially engaging online experience targeting vulnerable and older adults where future University live cultural offerings could benefit from a secondary virtual platform.

Principal investigator: Joy Doan, head of Marta and Austin Weeks Music Library

• Brief Cognitive-Behavior Therapy to Support Parent Coping during the COVID-19 Pandemic

Since parental stress during disasters or quarantine may be associated with child traumatic stress and/or subsequent incidents of abuse or neglect, this study will examine how parent-directed telehealth interventions using motivational, opposite action, and mindfulness strategies can be deployed during crisis situations to mitigate risk for parents exhibiting mental health concerns during our current COVID-19 pandemic.

Principal investigator: Jill Ehrenreich-May, professor of psychology

• Point-of-Care Oral Rinse Test for COVID-19

This project will enable the development of an oral rinse test that detects COVID-19 earlier and saves lives by directing resources and quarantine efforts to patients who need them most. Researchers will perform testing with the current prototype on a confirmed COVID-19 patient to determine the best antigen and concentration.

Principal investigator: Elizabeth Franzmann, associate professor of otolaryngology

• The use of a novel seroconversion assay to test high risk medical professionals for a history of SARS-CoV-2 exposure

This team will take blood samples from asymptomatic health care personnel working in any patient care capacity in three high-risk medical specialties—otolaryngology, anesthesiology, and ophthalmology—and examine them for the presence of immunity. The results could help South Florida hospitals consider strategies for resource and personnel deployment.

Principal investigator: Michael Hoffer, professor of otolaryngology and neurological surgery

• Effects of COVID-19’s Social Restrictions on Loneliness and Psychosocial Symptomatology

This team will gather data and insight on loneliness and other behaviors in the wake of CDC recommendations for social distancing during the COVID-19 pandemic. Results will demonstrate the effects of this public health crisis on loneliness, as well as other psychosocial symptoms. The team will also assist public health professionals in preparation for post-pandemic interventions and future global health emergencies.

Principal investigator: Viviana Horigian, associate professor of public health sciences

• Globalizing an Assay(test) for Inhibitors of the Main SARS-CoV-2 Protease

More than 20 models of the viral protease (which if targeted, might stop the virus) have been openly shared on Twitter, prompting labs around the world to begin a collective search for protease inhibitors. This project will provide a cheap, accessible screening test for characterizing potential protease inhibitors and use the available crystal structures to develop effective protease inhibitors through computational techniques.

Principal investigator: Daniel Isom, assistant professor, molecular and cellular pharmacology

• Detection of SARS-CoV-2 Virus in Tissue of Transplant Patients and Organ Donors

Researchers will investigate the ability to detect the COVID-19 virus in donor allograft tissue and frozen tissue. They will also attempt to determine whether the COVID-19 virus in the donor tissue is associated with transmission to the recipient and influences short- or long-term survival, as well as the health of the recipient.

Principal investigators: Hugo Kaneku Nagahama, assistant professor, surgery and Phillip Ruiz, professor of surgery and pathology and director of Transplantation Laboratories and immunopathology

• The Role of Community-Based Organizations in the Mitigation of COVID-19 Related Health and Educational Disparities

Partnering with Breakthrough Miami, a community-based academic enrichment organization for low-income students, this study  will contact families involved with this organization to understand the educational and health-related challenges as a result of COVID-19. Researchers will also investigate the role of community-based organizations in the mitigation of stress related to the concerns of infection and social distancing.

Principal Investigator: Laura Kohn Wood, dean and professor in the School of Education and Human Development.

• COVID-19 in Otolaryngology: Early Identification and Healthcare Worker Protection

Ear, nose, and throat (ENT) doctors play a key role in the treatment of COVID-19, but they are at high risk of exposure. This team will identify ENT issues in COVID-19 patients at the University of Miami and Jackson Memorial Hospital and evaluate new approaches to case identification and health care worker protection.

Principal investigator: Xue Liu, professor and Marian and Walter Hotchkiss Endowed Chair in otolaryngology

• Investigating the Protective Effects of Mindfulness Training in Older Adults during the COVID-19 Pandemic

Mindfulness training has emerged as an effective program to enhance cognitive functioning, improve psychological and physical health, and to reduce loneliness in young to mid-aged adults. But little is known about its effects in elderly adults. This proposal aims to offer mindfulness training via online delivery to elderly adults and to assess the training’s potential to protect against cognitive decline and degradation in psychological and physical health during the COVID-19 pandemic.

Principal investigator: Ekaterina Ninova (Denkova), research assistant professor, psychology

• Renin-Angiotensin-Aldosterone-System Inhibitors Impact on COVID-19 Infection

Individuals who have hypertension, diabetes, or underlying cardiovascular disease have higher rates of mortality from COVID-19 than the average person. Patients with these diseases have a high likelihood of being prescribed ACE inhibitors or angiotensin receptor blockers (ARBs) in order to treat their underlying ailments. This project will examine whether there is a link between drugs that are given to patients with hypertension, coronary artery disease, diabetes, or cardiovascular disease and the outcomes of COVID-19 patients.

Principal investigator:  Savita Pahwa, professor, microbiology and immunology

• Understanding the impact of COVID-19 on Maternal-Fetal Outcomes

This project aims to determine the rate of COVID-19 positivity among pregnant women and their newborns delivering at a tertiary care center in Miami with the highest rates of coronavirus in Florida. They also want to identify cases of maternal transmission of COVID-19, which is critical to establish treatment guidelines, while also answering questions about disease progression, perinatal transmission, and effects on the newborn.

Principal investigator: JoNell Potter, professor of clinical, obstetrics, gynecology, and reproductive services

• Increasing HealthCare workforce safety by 3D-printing novel N95 masks

This team will test, evaluate, and create new reusable mask designs for use in the health care setting to limit exposure and protect medical personnel and first responders who treat coronavirus patients. The aim is to provide masks to workers within the University of Miami and Jackson Memorial Hospital first. Finalized mask designs can be shared with other medical facilities.

Principal investigator: Carl Schulman, executive dean for research and professor

• Deep Learning Approaches for Analysis of Chest Radiographic Images of COVID-19 Cases for clinical management of the disease

This project hopes to develop a deep learning program that could classify X-ray or CT scan imaging characteristics in COVID-19 patients that could help radiologists categorize them into those patients who require hospitalization, those who will need Intensive Care Unit admission, and those at risk for death. In addition, such a deep learning network could be used to predict the patient’s response to current experimental drugs.

Principal investigator: Radka Stoyanova, research professor in radiation oncology

• Cardiac injury in COVID-19 patients

This project aims to understand the relationship between cardiac injury and COVID-19 severity. The team will conduct an extensive evaluation of 50 patients with a new COVID-19 infection who require hospital admission and will test myocardial injury and inflammatory biomarkers, use cardiac magnetic resonance imaging (CMR), and offer a social determinants of health survey. Blood will be saved for future biomarker discovery and genomic evaluation.

Principal investigator: Leonardo Tamariz, professor of medicine

• Defining the Interaction of SARS-CoV-2 with the Brain Endothelium

While respiratory distress dominates acute symptoms of COVID-19, ruptures in the brain’s capillary cells accompanied by bleeding within the brain have fatal consequences in patients with COVID-19. Moreover, impacts of COVID-19 on the brain depend largely on the ability of the SARS-CoV-2 virus to leak in through brain capillaries, the cells of which express the SARS-CoV-2 receptor (ACE2). This study is based on the hypothesis that interaction of the virus with ACE2 disrupts the normal barrier function of brain capillary cells, and induces inflammatory responses derived from these cells.

Principal Investigator: Michal Toborek, vice-chair for research and professor, biochemistry and molecular biology

• Developing a COVID-19 Early Detection, Tracking and Reporting System

Given the surfeit of social media data accompanying the recent outbreak of COVID-19, this group will take a computational and big data-driven approach to uncovering information about viral transmission, social sentiment and response, decision-making, and public health policy recommendations. The group proposes to develop algorithm(s), as well as an online early alert system, to provide early warnings for disease surveillance tied to geographical data.

Principal investigator: Nicholas Tsinoremas, director of the Institute for Data Science and Computing

• The Causes and Consequences of COVID-19 Misinformation

This team will investigate Florida citizens’ opinions on COVID-19, including their thoughts about the causes and consequences of the pandemic, their preferred sources of information, and subsequent behavior changes. They will also assess public perceptions of government responses to COVID-19 to determine how Floridians change their perceptions and behaviors over time in response to changing policies, messaging, and conditions—particularly if they or someone they know becomes ill. This will be one of very few studies to track a statewide population’s opinions, lifestyle factors, and health behaviors during an ongoing pandemic—with clear implications for policymakers, health communicators, and disaster specialists. 

Principal investigator: Joseph Uscinski, associate professor of political science

• COVID-19 Risk Behaviors and Transmission among Young Adults

Because young adults appear to experience fewer cases of the COVID-19 virus, this population may engage in behaviors that contribute to the spread of COVID-19. Yet, little is known about the impact of COVID-19 on adolescent mental and physical health and their substance-use behaviors. This project hopes to collect epidemiologic data on the patterns of mental and physical health, substance use (frequency and dose), and potential disease transmission behaviors among young adults during the COVID-19 pandemic.

Comments

[solarcane]

cool

[AeroCane]

WOW!
Very impressive
Thx for sharing

[solarcane]

check the news some health officials are now predicting a stronger second wave in the fall,I wonder if we will see football in awhile?

[UMike]

First?

[UMike]

Nope lol

[solarcane]

that was a good catch soup,
The title was sweet also

[86Cane]

stay safe guys please don`t let some government guy that wants to get reelected convince you everything is beautiful and getting better by the minute.

Posted by: solarcane | April 21, 2020 at 02:52 PM

Yoda says: Such a negative Nancy are you.

Stop preaching doom and gloom and death to all.

It is nowhere near as bad as you are projecting.

Lighten up Frances!

[solarcane]

osted by: 86Cane | April 21, 2020 at 06:17 PM

No sweat my friend,
We just see things different and tha's our right and our choices.
you know how that fake press blows everything up, I wouldn't believe a word of it I was you.
The fact that half the country is shut down is just a conspiracy hoax

In the mean time please stay safe soup I want you around to share some good times with when this crap is over

[86Cane]

In the mean time please stay safe soup I want you around to share some good times with when this crap is over.

Posted by: solarcane | April 21, 2020 at 06:31 PM

Me too. We will survive and live again.

Kayak, fish, football games and more! But don't get it Twisted Sister. Stop watching CNN and panicking. I will be at your house by morning. I like my eggs scrambled, hash browns crispy, coffee?

[AeroCane]

Sounds like a great breakfast and time!
Can I crash it? Lol

[86Cane]

Double-Blind, Randomized Study to Assess the Efficacy and Safety of Pulsed, Inhaled Nitric Oxide (iNO) in Subjects with Coronavirus Disease (COVID-19) Requiring Supplemental Oxygen

This team will evaluate the potential benefits of nitric oxide in treating COVID-19 utilizing the iNOpulse technology, which may potentially allow future patients to be treated outside of the hospital.

Principal investigator: Roger Alvarez, assistant professor of clinical medicine

NOTE: From research it appears that part of the problem with the disease is the lungs and thier ability to absorb O2. The other part is the blood's ability to carry O2 to important organs of the body (brain, heart, liver, kidneys, etc.) which can result in damage to these vital organs.

If you have heard about BEETS and their ability to enhance carrying O2 in the blood then you know about Nitric Oxide. Just a word to the wise.

https://www.humann.com/getsuperbeets-2-test/

[solarcane]

Good deal soup!

I didnt watch much tv till this stuff started, so now I watch about an hour a day of every news stations propaganda.
It makes you laugh at how close to 1970s used car salesmen every broadcaster is.
I have no favorites they all seem misguided by blind loyalty to someone or something that cares very little about what happens to them or their country.

[solarcane]

Nice heads up on BEETS.
I thought that was a New York band lol

[86Cane]

The Go-Gos

See the people walking down the street
Fall in line just watching all their feet
They don't know where they wanna go
But they're walking in time

They got the beat
They got the beat
They got the beat, yeah
They got the beat

See the kids just getting out of school
They can't wait to hang out and be cool
Hang around 'til quarter after twelve
That's when they fall in line

They got the beat
They got the beat
Kids got the beat, yeah
Kids got the beat

Go-go music really makes us dance
Do the pony puts us in a trance
Do the watusi just give us a chance
That's when we fall in line

'Cause we got the beat
We got the beat
We got the beat, yeah
We got it

We got the beat
We got the beat
We got the beat
Everybody get on your feet
We got the beat

We know you can dance to the beat
We got the beat
Jumpin',get down
We got the beat

Round and round and round
We got the beat
We got the beat...

[86Cane]

The Nitric Oxide Equivalent of 3 Whole Beets in 1 Easy Scoop

SuperBeets Can Help the Body:

Support Increased Energy & Stamina Without Added Sugar, Caffeine, or Stimulants

Support Healthy Blood Pressure Levels

May Support Respiratory Health Through Nitric Oxide Production

Promote Heart Health & Healthy Circulation

Provides Antioxidant Support With An Excellent Source of Vitamin C

[solarcane]

I had a pretty mad crush in Belinda

[86Cane]

No extra fees for the excellent advice.

All part of the best blog on da planet!

[86Cane]

Belinda was a beauty. No doubt about that!

[solarcane]

My daughters a nurse for the VA in North Carolina
They have sign that says

"Fools rush in where ambulances fear to tread."

[solarcane]

Belinda was a beauty. No doubt about that!

Posted by: 86Cane | April 21, 2020 at 09:12 PM

This is a true fact I'm pretty embarrassed to admit.

When the Go Go's sang Are Lips Are Sealed I thought they were saying Arlington Field for about a month.
My wife reminded me that I was a
moron several times as I remember

[86Cane]

My other recommendation:

https://www.walgreens.com/store/c/nature%27s-way-sambucus-gummies/ID=prod6388362-product

Details

TRIPLE ACTION IMMUNE BLEND*: Sambucus elderberry gummies are made from European black elder (Sambucus nigra L.) has been traditionally used as a winter remedy for immune support.* Made with our unique, full spectrum black elderberry extract, ensuring Flavonoid BioActives content, which has been tested and shown to be active within the body.

PREMIUM ELDERBERRIES: Elderberry gummies are made from a unique cultivar of black elderberries with a higher level of naturally-occurring flavonoids; each serving delivers 50 mg of black elderberry extract, vitamin C and Zinc.

STANDARDIZED BIOACTIVES: Full-spectrum black elderberry extract is standardized to anthocyanins, which are potent flavonoid BioActives. TESTED FOR BIOAVAILABILITY: Our elderberry extract has been tested for bioavailability and activity within the body.

NATURAL FORMULA: This immune system booster has no artificial colors, flavors or preservatives and is gluten free and kosher certified. *These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

[solarcane]

No extra fees for the excellent advice.

All part of the best blog on da planet!

Posted by: 86Cane | April 21, 2020 at 09:11 PM

I think when football starts up we will put together a little donation drive to give back a couple bucks each for having Canespace as a part of our day, I think everyone would agree to that.

[86Cane]

Build the immune system. And worry not.

70% of your immune system is in your gut. Eat good yogurt, drink probiotics, take probiotic supplements. Multiple types and kinds.

[solarcane]

Good advice soup,
We have used a Vitamix for years we use a lot of yogurt,bananas,blueberries,coconut water and lots of other goodies.
There is a lot to be said for diet exercise and sleep for sure.
I need to shed about ten or fifteen tho.
Stay safe I'm out

[BigWindyCane1]

Another Great post Soup! Highlighting Canes on the front lines of research related to COVID-19! Canes will continue to make their mark, and in this case, help save this world from global catastrophe!

Just a few more outstanding Canes doing great things and making a lasting impact—this is how we roll❗️

[86Cane]

Just a few more outstanding Canes doing great things and making a lasting impact—this is how we roll❗️

Posted by: BigWindyCane1 | April 21, 2020 at 10:53 PM

Yes Sir, that's how we roll!

Solving the world's problems one at a time.

[BigWindyCane1]

This Lashlee quote makes me optimistic:

“....[The first year at Auburn] There were not a lot of positives being said. We were bad all spring and summer, but we just came in as a coaching staff and tried to focus on what we had.

“We tried to focus on what they did well. We had no idea--we were hoping to go to a bowl game and we ended up playing for the national championship so you never know what can happen, but we were excited with the guys we have because we liked their energy level and how much they were buying into what we were doing and that excites us.”

[Harry Miller]

I have been drinking supper Beats for years plus eating beats and putting the greens in a salad or cooking the like I cook collard greens,
instead of throwing them out. They are packed with
High amounts of vitamins and nutrients,including Iron , calcium, protein,,magnesium, zinc and fiber.
Fights inflammation,,improves digestive health, supports brain health and contain anti-cancer properties. Beats are a supper food. I love beats.

[Harry Miller]

I take a lot of herbs including Elderberries which is one of the most commonly used medicinal plants in the world.One of the most taken supplements to treat cold and flu symptoms. Just don't eat raw berries, the bark or leaves. They can be poisonous
and cause stomach problems.

86 I am with you on every thing you said. I also take ActivOX a NITRIC OXIDE FORMULA. A losinger.

[pb]

Anyone have thoughts on dingleberries?

[roachcane77]

Beware a second wave.

Hey, I'm sick of this mess as much as anyone, and the economy and small businesses are getting CRUSHED by this pandemic. But those NOT on the front lines are NOT seeing the REAL facts, and if you believe this is "just another" flu season... It's NOT!

Coronavirus Kills More Americans in One Month Than the Flu Kills in One Year

Good article from the National Review... (I don't consider myself a "conservative" like many of you guys), but from a leading conservative publication... https://www.nationalreview.com/2020/04/coronavirus-kills-more-americans-in-one-month-than-the-flu-kills-in-one-year/

Check out the article... and STAY VIGILANT!

[roachcane77]

The "chart" from this article showing specific comparisons of THIS virus vs. "other" major killers is also explained better here:

https://www.thenewatlantis.com/publications/not-like-the-flu-not-like-car-crashes-not-like

[roachcane77]

Be sure to go to the bottom of The New Atlantis article where the LATEST UPDATED charts are included...

This is REAL folks.

[Terrance M Sullivan]

The Best Damn Blog On The Planet. Thank God I luckily found Canespace by Default at the Hampton Inn Fort Lauderdale/Plantation in November 19th,2010 the night before the Virginia Tech Game! Crazy how you get to meet people they become friends, then become Family. Can't Believe It's Been a Decade this upcoming November! Love U All and Thank U For The Tips!

[roachcane77]

The Best Damn Blog On The Planet.
Posted by: Terrance M Sullivan | April 22, 2020 at 10:57 AM

AGREE!! 💯💯

[solarcane]

roach
don't make major a big deal its only killed 45,150 Americans and a mere
179,725 human beings don't be so negative.

You know how I truthfully feel, we are dealing with the least qualified governor to handle a disaster in America, so its even worse here.
Do what you do my friend

[solarcane]

Posted by: Terrance M Sullivan | April 22, 2020 at 10:57

I remember when you very first started posting,
You were and are very polite and a knowledgeable guy I have always enjoyed reading your stuff,
You are dear to me stay safe brother,

[solarcane]

Happy Earth Day everyone
I would say go outside but do what you know is safe

[Terrance M Sullivan]

Thank You Solar I appreciate U Brotha!

[pb]

Posted by: solarcane | April 22, 2020 at 11:46 AM

Have nothing but respect for you sir, but last year over 600,000 people in this world died from the flu last year and literally no one said a word.

[solarcane]

pb thanks for that,

in my opinion I have never had flu like this.
We have been friends for over a decade and we don't always agree, but I respect your take on subjects too.
I hope you and your family stay healthy

[alpine]

- best estimates in the usa since 2010: 12,000 - 61,000 deaths annually
- global estimates: 290,000 - 646,000 deaths annually
(some flu seasons hit harder than others, obviously)

the above facts are without social distancing!!
. . . the coronavirus would be a totally different animal if everyone just went about their normal business
. . . the usa would be skyhigh above the (to-this-point) 45,000 deaths if we hadn't already put into motion lockdowns & social distancing!!!

- northern italy showed what happens when a government reacts too late and the hospitals are overwhelmed

- that said, we are slowly gearing up here in west austria;
- all stores are back . . . but you sometimes have to wait a while to get in, cause only so many are allowed in and everyone wears masks
. . . schools & restaurants & cultural events are all still on hold

- if people go by the guidelines, i think you can slowly reopen places that are not being hit real hard, but it's really a case-by-case situation (more per city or area code than state . . . and certainly no opening can be done on a federal level)

[86Cane]

Beats are a supper food. I love beats.

86 I am with you on every thing you said. I also take ActivOX a NITRIC OXIDE FORMULA.

Posted by: Harry Miller | April 22, 2020 at 03:45 AM

Wise man that Harry Miller.

[86Cane]

Here's another "recommendation":

If you have been home and haven't been going ANYWHERE over the last few weeks you are going to want to start your car and drive a round the neighborhood at least once a week. Cars, just like boats, do not like to sit unused for long period of time. Oil, gas, batteries and tires all must be taken care of by driving once in a while.

You are welcome.

[solarcane]

Posted by: 86Cane | April 22, 2020 at 04:12 PM

Post a comment

Upped the public service messages considerable thanks Captain

[solarcane]

Allan Haye Chaminade D line commits to Miami today

[alpine]

herb: new dl; what's the word?

[HerbieIbis]

Alpine, not a bad addition, the only problem the dude is about 6'1. If we were running a three four defense, he would be a nice nose guard.
We need a couple big time LB'S more than we need any thing else aside from getting the numbers right at CB!

[HerbieIbis]

Get Leonard Taylor's nose out of the Gators azz hole, then we are set for some years. We scoop Taylor, then Collins stays put. Only thing keeping Collins committed is momma.

[MLALUMNI1970]

Thank you 86 fir the car info. I am going to drive my car tomorrow. I do have cabin fever like everyone else. I am originally from Michigan, which has it much worse than Florida. I hope everyone follows the rules to stay safe, and I am NOT talking about having sex. You are all on your own for that.
Pray that all of you CANES remain virus free.
GO CANES, always.